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70 HP 150 5-AMINO-1MQ Small-molecule NNMT inhibitor body-composition research ALIASES 5A1MQ, 5-amino-1-methylquinolinium iodide, NNMT inhibitor CLASS Small-molecule NNMT inhibitor (not a peptide) FORMULA C10H11IN2 HALF-LIFE Short plasma half-life (oral bioavailable) ROUTES Oral (in animal studies) Subcutaneous (research) MECHANISM OF ACTION 5-Amino-1-methylquinolinium iodide

Table 7: Bleeding ain Deep Vein Thrombosis and Pulmonary Embolism Treatment Studies a Bleeding rates are during the study drug treatment period (approximately 7 days)

Furthermore, RS may disrupt proteasomal degradation pathways, resulting in the accumulation of damaged proteins [33] ( Table 1 )